Generic GPCR residue numbering

A paper on generic residue numbering schemes for GPCRs has been published in Trends Pharmacol. Sci.

The paper reviews commonly used generic numbering schemes, and introduces a novel, structure-based scheme that accounts for structural irregularities revealed by recent GPCR crystal structures.

Complementary tools to look up generic numbers and number PDB structures can be found in GPCRdb.

Read the paper HERE.